Natura-Tec Riviera News | Nature’s Answer to Chronic Inflammation and Aging

Revolutionizing Anti-Aging with Natura-Tec CrystalRose™

Natura-Tec, renowned for its sustainable and efficacy-driven cosmetic solutions, proudly presents the latest edition of Riviera News featuring CrystalRose™. This groundbreaking biomimetic active ingredient is designed to combat skin aging by addressing the underlying issue of chronic inflammation, a primary contributor to age-related skin damage.

The Anti-Inflamm’Aging Powerhouse

As skin ages, its ability to manage inflammatory stress diminishes, leading to persistent inflammation and subsequent aging. CrystalRose™ is engineered to stimulate the skin’s production of resolution mediators, molecules crucial for deactivating chronic inflammation. This proactive approach not only prevents aging but also fortifies the skin’s natural defenses against time-related damage.

natura tec crystal rose inflammation + aging relationship

Biomimetic Excellence and Sustainable Development

CrystalRose™ is produced using a patented closed-circuit photobioreactor process, ensuring consistent quality and minimal environmental impact. Its formulation includes key components:

Evening Primrose Seed Oil
  • Exceptional high content in linoleic acid (LA) (70–74%)
  • γ-linolenic acid (GLA) (8–10%), both precursors of anti-inflammatory eicosanoids
  • Reduction of Inflammatory mediators such as IL1β,IL6, and Tnα
  • GLA also in hibitsLOX 5 enzyme ,reducing pro-inflammatory Leucotriènes (LTB4)
  • Sterols
TRIOLEIN
  • Upcycled byproduct from olive oil refining
  • An active, pure and stable omega-9 excipient, that boosts and preserves the effectiveness of H. Pluvialis
  • Helps to deeply protects the skin
HAEMATOCOCCUS PLUVIALIS
  • ASTAXANTHIN
  • The king of carotenoids—A strong skin protectant
  • Potent skin antioxidant and anti-inflammatory molecule
  • Protection against oxidative stress
  • Stimulates anti-inflammatory cytokines IL1R,IL4,10 & 11
  • Inhibits pro-inflammatory cytokines IL1β, IL6 and TNFa and PGE2 after UV radiation
  • Inhibits collagenase, MMP activity
EPA – EICOSAPENTANOIC ACID
  • Pro resolution agent that fights against cellular senescence
  • Lipid precursor of Specialized Pro-resolving Mediators (SPM) : E Serie Resolvins family
  • Tissular homeostasis
  • Skin regeneration stimulation

Clinical Insights and Efficacy

Enhancing Skin’s Natural Resolution Mechanisms

Natura-Tec CrystalRose™ has shown significant efficacy in stimulating the production of specialized pro-resolving mediators (SPMs), which are crucial for ending inflammation and initiating tissue repair. The clinical study focused on quantifying resolvins, a subset of SPMs, in skin explants treated with CrystalRose™.

crystalrose pro resolution activity resolvins quantification– results

Natura-Tec CrystalRose™ has shown significant efficacy in stimulating the production of specialized pro-resolving mediators (SPMs), which are crucial for ending inflammation and initiating tissue repair. The clinical study focused on quantifying resolvins, a subset of SPMs, in skin explants treated with CrystalRose™.

Inhibiting Chronic Inflammatory Pathways

In addition to promoting resolution, CrystalRose™ exhibits potent anti-inflammatory properties by reducing the levels of pro-inflammatory mediators. The study quantified several key pro-inflammatory molecules in skin explants subjected to inflammatory stimuli and treated with CrystalRose™.

crystalrose anti inflammatory activity– proinflammatory mediators quantification results

These reductions indicate that CrystalRose™ effectively interferes with chronic inflammation pathways, acting as a switch-off mechanism to mitigate prolonged inflammatory responses.

Comprehensive Anti-Inflammation and Resolution Enhancement

The study also evaluated the global impact of CrystalRose™ on the three primary pathways of inflammation and resolution: arachidonic acid (AA) pathway, eicosapentaenoic acid (EPA) pathway, and docosahexaenoic acid (DHA) pathway.

crystalrose global impact of the active on the 3 activation pathways aa (proinflammatory mediators) – epa & dha (resolution mediators)

The data, normalized for comparative analysis, reveal that CrystalRose™ not only reduces pro-inflammatory mediators but also actively enhances the production of resolution mediators from the EPA and DHA pathways. This dual-action reinforces CrystalRose™’s capability to both decrease inflammation and promote the resolution phase, thus restoring skin homeostasis and function.

A Revolutionary Approach to Anti-Aging and Skin Health

Natura-Tec CrystalRose™ is a revolutionary ingredient that addresses skin aging through a multifaceted approach. By significantly enhancing the production of resolvins, inhibiting pro-inflammatory mediators, and positively impacting the critical pathways of inflammation and resolution, CrystalRose™ stands out as a comprehensive solution for anti-aging skincare.

For formulators seeking to create products that offer robust anti-inflammatory and pro-resolution benefits, CrystalRose™ provides an unparalleled active ingredient. Explore the transformative potential of CrystalRose™ with Deveraux Specialties and elevate your skincare formulations to new heights. For more details and inquiries, contact your sales representative or submit a request below.

Riviera News | Natura-Tec CrystalRose™
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