Cracking the Code of Skin Moisture with MultiMoist CLR™
Moisturizers are staples in daily skincare routines, but their scientific complexity often goes unnoticed. Among the array of available hydrating agents, MultiMoist CLR™, developed by CLR Berlin, stands out for its innovative mechanism and multifaceted benefits. This blog explores the science behind MultiMoist CLR™, unraveling its unique role in addressing one of modern skincare’s most significant challenges—maintaining optimal hydration and leveraging the skin’s own biology.
The Hydration Challenge: More Than Just Surface Moisture
Hydration is more than a feeling; it’s a physiological state crucial to skin health. Dry skin, characterized by diminished elasticity, dullness, and discomfort, often results from impaired production of the Natural Moisturizing Factor (NMF). NMF molecules, primarily derived from the protein filaggrin, are vital for maintaining water content within the stratum corneum—the skin’s outermost layer.
MultiMoist CLR™, a potent blend of fructooligosaccharides and Beta Vulgaris (Beet) Root Extract, which enhances the production and activation of the Vitamin D Receptor (VDR). This activation is critical for epidermal differentiation, leading to increased filaggrin production and, consequently, improved hydration.
Decoding Vitamin D’s Role in Skin Hydration
Vitamin D is traditionally associated with bone health, but its significance extends to skin physiology. MultiMoist CLR™ operates in synergy with Vitamin D, amplifying its effects through VDR activation. This unique interaction enhances the skin’s barrier function and hydration levels, even in individuals with limited sun exposure—a common cause of Vitamin D deficiency.
Evidence from the Lab: In Vitro and In Vivo Insights
► In Vitro Findings
Studies demonstrate that MultiMoist CLR™ increases VDR expression by up to 38.8% and its activation by 23.3%. These improvements accelerate critical epidermal processes like ATP production and cAMP synthesis, boosting skin’s energy levels and promoting a healthy differentiation cycle.
► In Vivo Efficacy
Testing the ingredient’s performance in real-world conditions reveals remarkable results. MultiMoist CLR™ shows:
1) Immediate and Long-Term Hydration: MultiMoist CLR™ demonstrated an impressive 30% increase in skin hydration within two hours after a single application. Long-term use over 21 days showed sustained moisture retention, outperforming placebo and even benchmark moisturizing actives
2) Reduction in Visual Dryness: Squametry tests revealed a significant reduction in visible dryness by 12–14% after consistent use, highlighting MultiMoist CLR™’s ability to improve the skin’s appearance
3) Skin Smoothness Enhancement: Skin smoothness, a key parameter in consumer satisfaction, improved dramatically after using MultiMoist CLR™. Measurements conducted using Primos® high-resolution technology showed an 8–10% increase in skin smoothness within two hours, indicating that MultiMoist CLR™ not only hydrates but also enhances the tactile quality of the skin
4) Consumer Perception: Participants reported noticeable improvements in the look and feel of their skin, validating the objective data. Over 70% of volunteers noted smoother, softer skin just 24 hours post-application
How far do you judge the formulation to make your skin feel smoother?
How do you judge the moisturizing effect of the formulation?
How far do you judge the formulation to improve the look of your skin?
Beyond Moisturization: Multifunctionality at Its Best
MultiMoist CLR™ is not confined to skincare. In haircare, it addresses six critical aspects, from reducing frizz to preventing breakage, proving its versatility across cosmetic formulations. Its prebiotic properties further enhance its appeal, supporting a healthy skin microbiome by fostering beneficial bacterial growth.
► Multifunctional Efficacy for Hair:
1. Moisture Retention in Hair Cortex: MultiMoist CLR™ binds water within the hair cortex, enhancing moisture retention. This hydration improves hair elasticity and resilience, leading to healthier-looking hair.
2. Conditioning and Combability: By improving hair’s moisture content, MultiMoist CLR™ acts as an effective conditioner. It enhances combability, reducing the effort required to detangle hair and minimizing mechanical damage during styling.
3. Protection Against Color Fading: Repeated washing can cause hair color to fade. MultiMoist CLR™ helps protect against this by maintaining the hair’s moisture balance, which preserves color vibrancy over time.
4. Reduction of Hair Breakage: Enhanced moisture retention and improved combability contribute to a significant reduction in hair breakage. By strengthening the hair shaft, MultiMoist CLR™ minimizes damage caused by daily grooming practices.
5. Control of Static Flyaway: Static flyaway is a common issue, especially in dry conditions. MultiMoist CLR™ effectively reduces static electricity in hair, leading to smoother, more manageable strands.
6. Reduction of Hair Frizziness: By maintaining optimal moisture levels and improving hair structure, MultiMoist CLR™ significantly reduces frizz, resulting in smoother and more polished hair appearance.
► Recovery of Microbial Diversity:
MultiMoist CLR™ demonstrates significant prebiotic effects on the skin microbiome, particularly in recovering microbial diversity and modulating the distribution of key bacterial phyla:
After inducing microbial imbalance via tape stripping, MultiMoist CLR™ (3%) was applied twice daily for seven days on 17 volunteers with normal skin. The microbial diversity of untreated, healthy skin was set as the baseline (100%).
Mapping the Moisturization Puzzle
MultiMoist CLR™ exemplifies the fusion of nature and science, offering a comprehensive solution to the moisturization puzzle. By leveraging the skin’s biological pathways, it delivers both immediate and sustained hydration while addressing the broader challenges posed by modern lifestyles. As consumer demand for multifunctional, effective products grows, MultiMoist CLR™ positions itself as an indispensable ingredient in the future of cosmetic science.
