Hydration: The Key to Beautiful Skin

Hydration is Key: The Role of Hyaluronic Acid

Hydration remains a top priority for consumers, with the majority seeking products that promise and deliver on this essential skin benefit. Studies show that hydration and nourishment are the most desired benefits among beauty care users, with at least +17.9K average monthly searches.*​ Hyaluronic Acid (HA) has long been celebrated as a hero ingredient in the realm of skincare for its impressive hydration properties. However, while HA is exceptionally effective in leave-on products, it faces limitations in rinse-off formulations, and its benefits, though immediate, are not long-lasting.

The Limitations of Traditional Hyaluronic Acid

Hyaluronic Acid is renowned for its ability to hold up to 1000 times its weight in water, making it a top choice for hydrating formulations. Yet, traditional HA struggles in two main areas:

Rinse-Off Formulations

The hydrating effects of HA do not withstand the rinse-off process, rendering it less effective in products like shampoos and body washes.

Longevity of Benefits

While HA provides an immediate moisture boost, the hydration it offers diminishes relatively quickly, necessitating frequent reapplication.

These limitations have driven the need for innovation to enhance HA’s performance across different product formats and extend its hydrating benefits.

Introducing the New 3rd Generation HA

Givaudan Active Beauty has developed an advanced solution that overcomes the traditional limitations of HA. The third-generation hyaluronic acid, PrimalHyal™ Hydra[+], redefines the gold standard for hydration. This innovative ingredient delivers long-lasting hydration, effective in both rinse-off and leave-on formulations, providing comprehensive benefits that traditional HA could not achieve.

PrimalHyal™ Hydra[+] offers several groundbreaking advantages:
Long-Lasting Hydration

Delivers sustained moisture retention, enhancing skin hydration over extended periods.

Rinse-Off Formulation Compatibility

Unlike traditional HA, PrimalHyal™ Hydra[+] retains its hydrating properties even in rinse-off products, making it ideal for shampoos, conditioners, and body washes.

Enhanced Benefits in Leave-On Formulations

Supercharges the hydrating effects in leave-on products, ensuring deeper and longer-lasting skin moisturization.

The Science Behind PrimalHyal™ Hydra[+]

primalhyal hydra+ mechanism of action

The unique efficacy of PrimalHyal™ Hydra[+] stems from its low molecular weight and high cationization. This structure allows for better adhesion to the skin surface, significantly improving hydration even after rinsing. Clinical studies have demonstrated that PrimalHyal™ Hydra[+] significantly boosts skin water content, reinforcing the skin barrier and enhancing overall skin hydration compared to regular HA.

Efficacy in Rinse-Off and Leave-On Applications

PrimalHyal™ Hydra[+] has been rigorously tested to validate its efficacy in both rinse-off and leave-on formulations. The clinical results underscore its superior performance in providing long-lasting hydration and reinforcing skin barrier function.

Rinse-Off Applications

Traditional hyaluronic acid often fails to deliver lasting benefits in rinse-off formulations, such as shampoos, body washes, and shower gels. However, PrimalHyal™ Hydra[+] overcomes this challenge with remarkable results:

Perfect skin adhesion properties

Studies show that PrimalHyal™ Hydra[+] significantly improves skin adhesion, ensuring that its hydrating properties remain effective even after rinsing. This was demonstrated through skin explant tests where PrimalHyal™ Hydra[+] retained its presence on the skin surface post-rinsing, unlike regular hyaluronic acid which washed away easily.

primalhyal hydra+ skin adhesion
Barrier Function Reinforcement

PrimalHyal™ Hydra[+] has been shown to increase the production of key proteins involved in skin hydration and barrier function, such as aquaporin and filaggrin. This reinforces the skin’s natural barrier and enhances overall hydration, even in rinse-off conditions​.

primalhyal hydra+ reinforcement of barrier function and skin hydration
Increase of skin hydration

In a clinical study involving 29 women with dry skin, a shower gel containing PrimalHyal™ Hydra[+] was applied to one calf, while a placebo was applied to the other. The results showed a significant improvement in skin hydration after just one shower, with an 11.% increase in moisture levels compared to the placebo.

primalhyal hydra+ skin hydration

Leave-On Applications

In leave-on formulations, PrimalHyal™ Hydra[+] not only matches but surpasses the performance of high molecular weight hyaluronic acid, traditionally considered the gold standard for hydration:

Improvement of skin coverage by hyaluronic acid

The positively charged structure of PrimalHyal™ Hydra[+] allows for better coverage of the skin surface, providing a more uniform and effective hydration layer. Scanning electron microscopy (SEM) images revealed that PrimalHyal™ Hydra[+] forms a smoother and more homogenous film on the skin compared to regular hyaluronic acid​.

primalhyal hydra+ skin coverage
Instant moisturizing gratification improving over time

Clinical studies involving 40 women with dry skin demonstrated that PrimalHyal™ Hydra[+] significantly increased skin hydration levels by 19.8% after 6 hours in the initial application, with benefits building up over time. After one week of use, skin hydration increased by up to 29.3%, more than twice the efficacy of the placebo.

primalhyal hydra+ instant and long term moisturization
Flash moisturizing and long-lastingness

In a study using sheet masks, PrimalHyal™ Hydra[+] showed immediate hydration benefits, increasing skin water content by 70% after just one application. The hydration effects were sustained, with a 40% increase in skin water content four days after the last application.

primalhyal hydra+ flash moisturizing
Barrier Reinforcement

PrimalHyal™ Hydra[+] significantly enhances the stratum corneum thickness and increases the content of lipids and proteins in the skin, reinforcing the skin barrier. This contributes to longer-lasting hydration and improved skin health​.

primalhyal hydra+ skin barrier reinforcement lipids and proteins
primalhyal hydra+ stratum corneum

Setting New Standards in Skin Hydration

PrimalHyal™ Hydra[+] demonstrates exceptional clinical efficacy in both rinse-off and leave-on applications. Its ability to deliver and maintain hydration in rinse-off products is groundbreaking, providing benefits that traditional hyaluronic acid cannot. In leave-on formulations, PrimalHyal™ Hydra[+] offers superior skin coverage, long-lasting hydration, and enhanced skin barrier function. This innovative ingredient sets a new standard for hydration in skincare, meeting consumer demands for both immediate and enduring benefits.

For more detailed information about PrimalHyal™ Hydra[+], download the product flyer and request a sample below. If you have any questions or need further assistance, please reach out to your designated sales representative.

PrimalHyal™ Hydra[+] Flyer
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