DL CERAcalm: Addressing the Challenges of Ceramides in Skincare
Ceramides, integral lipids that form the skin’s natural barrier, are indispensable for maintaining hydration, resilience, and protection against environmental stressors. They comprise roughly 50% of the epidermis, underscoring their importance in skincare. Yet, as we age, our natural ceramide production declines significantly—by up to 40% in our 30s and 60% by our 40s. This depletion is linked to visible signs of aging, such as dryness, fine lines, and a compromised barrier that is less equipped to retain moisture.
Formulating with ceramides has long been the gold standard for addressing these challenges. However, their application comes with significant limitations.
The cosmetic and personal care industry has long sought a solution that addresses these challenges without compromising performance. Enter DL CERAcalm, a breakthrough ingredient that redefines how we approach ceramide support in skincare formulations.
The Innovation Behind DL CERAcalm
DL CERAcalm is a lipid-soluble, plant-derived cosmetic ingredient extracted sustainably from the Indian kino tree (Pterocarpus marsupium). Unlike traditional ceramides, DL CERAcalm doesn’t merely supplement the skin; it works by promoting and modulating the biosynthesis of ceramides within the epidermis. This innovative mechanism bypasses the limitations of topical ceramides, offering formulators a more effective and reliable solution.
Key Features:
Evidence-Based Benefits
► Ceramide Stabilization
In studies using reconstructed human epidermis models, DL CERAcalm maintained normalized levels of both short-chain and long-chain ceramides. Unlike other actives such as Vitamin A and Vitamin C, which can deplete ceramide levels, DL CERAcalm preserved skin’s natural balance.
► Inflammation Control
Inflammation-induced ceramide disruption is a hallmark of conditions like eczema. DL CERAcalm, especially in combination with niacinamide, significantly suppressed the impact of inflammatory cytokines, normalizing ceramide levels in skin models.
► Accelerated Barrier Function
DL CERAcalm-treated skin showed increased ceramide content and filaggrin expression, markers critical for effective skin barrier repair. This reinforces its utility for addressing dry, compromised, or aging skin.
Accelerated Barrier Repair – Ceramides
Accelerated Barrier Repair – Filaggrin
Formulation Opportunities
DL CERAcalm is a versatile ingredient designed for a wide range of skincare applications:
- Hydrating and Moisturizing Products: Combine with humectants or occlusives for optimal hydration.
- Anti-Aging Solutions: Pair with ceramides, Vitamin A, or peptides for improved elasticity and hydration.
- Sensitive Skin Care: Use in OTC formulations targeting eczema or severely dry skin.
Formulation Guidelines:
- Recommended use level: 1–3% by weight.
- Suitable for emulsions, anhydrous systems, and functional makeup.
- Process tolerance: Stable up to 65°C for short durations.
Bridging Science and Consumer Needs
The growing demand for multifunctional skincare—products with fewer ingredients yet greater efficacy—has made innovation more critical than ever. DL CERAcalm meets this demand head-on. By enhancing ceramide biosynthesis, it provides formulators with a powerful tool to create products that deliver real, measurable benefits. Its versatility allows for seamless integration into diverse formulations, from simple moisturizers to high-performance anti-aging treatments.
At Deveraux Specialties, we are proud to present DL CERAcalm as a solution to one of the industry’s enduring challenges. By empowering skin to produce its own ceramides, DL CERAcalm redefines what’s possible in skincare innovation—delivering healthier, more resilient skin for consumers everywhere.
Footnotes:
Zhang Q, Flach CR, Mendelsohn R, Mao G, Pappas A, Mack MC, Walters RM, Southall MD. Topically applied ceramide accumulates in skin glyphs. Clin Cosmet Investig Dermatol. 2015 Jul 1;8:329-37. doi: 10.2147/CCID.S83857. PMID: 26170709; PMCID: PMC4493983.
