DandErase™ is a natural, microbiome-friendly anti-dandruff solution powered by bioactive compounds from Crocus sativus L (saffron flower). Developed through green fractionation and NaDES technology, it effectively targets Malassezia, the primary cause of dandruff, while maintaining scalp microbiome balance. DandErase™ provides clinically proven anti-inflammatory, anti-itch, and scalp barrier-restoring benefits, delivering results comparable to leading anti-dandruff actives without disrupting the scalp’s natural ecosystem. Designed for rinse-off and leave-on applications, it offers a sustainable, high-performance alternative for scalp care formulations.