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AnnonaSense CLR™, derived from the exotic Annona cherimola fruit, offers formulators a multi-faceted approach to skin wellness by targeting the endocannabinoid system via CB2 receptor activation. This unique mechanism not only mitigates inflammation and stress markers like TRPV1, Histamine, and TNF⍺, but also down-regulates IL-31RA expression, making it a comprehensive ingredient for reducing skin sensitivity and itch. Its adaptogenic properties work to restore skin’s homeostatic balance, resulting in enhanced skin appearance and an overall improvement in the perception of well-being and quality of life.
